The ability of synapses to weaken or strengthen over time in response to the decrease and increase in their activity is referred to as synaptic plasticity. It is one of the significant neurochemical foundations in memory and learning because memories are suggested to be represented by interconnections of neural circuits in the brain. Plastic change is a result of the alterations in the number of neurotransmitter receptors present on a synapse. Several mechanisms take place and cooperate in order to achieve synaptic plasticity. Some of these are alteration in the quantity of neurotransmitters releasing into a synapse, and alteration in the effectiveness of cells responding to these neurotransmitters. The topics covered in this extensive book deal with the core subjects of synaptic plasticity. It brings forth some of the most innovative concepts and elucidates the unexplored aspects of synaptic plasticity. The extensive content of this book provides the readers with a thorough understanding of the subject.