Didymus of Alexandria (also known as Chalcenterus, ‘bronze-guts’, for his outstanding ability to ‘digest’ and rework the scholarship of his predecessors) played a pivotal role in the understanding and reception of many classical Greek authors, both in antiquity and in modern times. His commentaries on the comic playwrights influenced ancient and modern scholarship alike and constitute to this day an invaluable repository of information for the study of ancient Greek comedy, the history of Hellenistic philology, and more. This is the first critical edition (with English translation and commentary) of all the extant fragments of Didymus’ commentaries on the comic playwrights.