Structure and Evolution of Single Stars: An introduction is intended for upper-level undergraduates and beginning graduates with a background in physics. Following a brief overview of the background observational material, the basic equations describing the structure and evolution of single stars are derived. The relevant physical processes, which include the equation of state, opacity, nuclear reactions and neutrino losses are then reviewed. Subsequent chapters describe the evolution of low-mass stars from formation to the final white dwarf phase. The final chapter deals with the evolution of massive stars.