Structural biology is an interdisciplinary field which incorporates concepts of biochemistry and molecular biology to study and analyze biological structures such as nucleic acids and proteins. This book discusses the fundamental as well as modern approaches to understand structural biology with particular emphasis on macromolecules. It explains in detail some existent theories as well as innovative concepts revolving around structure of protein networks, application of atomic and molecular data and computational modelling. The aim of this book is to present researches that have transformed this discipline and aided its advancement. Scientists and students actively engaged in this field will find this book full of crucial and unexplored concepts.