In this book, the authors present current research in the study of the anatomy, functions and role in disease of the striatum. Topics discussed include the localisation, processing and function of cholinesterases in striatum; impaired nigrostriatal dopaminergic neurotransmission in Huntington's disease; behavioural and neurochemical interrelations between the striatum and the cerebellum; striatal dysfunction and social cognition and the effects of experience on striatal morphology.