This book is a safety resource for the parent or adult preparing to conduct hands-on science activities. It contains information on basic safety philosophy as well as tips and tools for helping the adult evaluate and conduct hands-on activities. The resource is intended to be used in conjunction with science activity books and/or science curriculum. While the book was designed for primarily parental or one-on-one involvement, it can be used in cooperative school, classroom or demonstration settings. Supplemental resources have been prepared by the author to assist the user with further safety evaluations of future projects.