The year is 2022. The conflict between the worldwide nations of humanity and the superhuman Bearer Houses is about to break out after a long stalemate, the people in an uneasy state. Haruka Mantsu, a beautiful nurse known as the "Angel of Nagasaki", had been kidnapped by the most notorious and most wanted Bearer in the world, the man known only as "Sorrow"...the very same man who had killed her friend, Nao Naga, right in front of her. She awakens in a mysterious place after near-drowning in Tokyo Bay attempting to flee from Sorrow, unaware of where she is, or how important she is to the course of the war....