After three years in Mississippi State Penitentiary, Carl O'Donell re-enters society with simple plans - get back to work pushing drugs and keeping an eye on his younger brother Jimmy. He quickly learns that not only has Jimmy been committed after yet another failed suicide attempt, but his old boss is dead at the hands of Mexican drug lord Armando Vega. Carl's only way to quick cash and a fresh start is through Armando. He hires Carl for a simple assignment of busting up a rival meth lab that turns complicated and deadly. Now Carl and Jimmy are on the run from the Mexican drug cartel as well as the police after a messy robbery. It would be a lot harder to find them if they didn't leave so many bodies in their wake.