Along with the deaths of Arthur Rhodes and his henchmen, comes a time of security and well-being to the Arkansas Valley in general and The Bartlett Ranch in particular, that has now been renamed Shiloh. As Clint and Sue embark on a rewarding and fruitful life together as husband and wife, they are quickly blessed with two wonderful but mischievous children, Chad and Rebecca. With the railroad now drawing ever closer to becoming a reality, old wounds are reopened because of the greed of an unscrupulous man named Heywood Jensen, who will stop at nothing to gain complete control of the ranch. As proof of that, he hires on a handful of gunfighters who are not only a very real threat to Clint, Jimmy, and Two Buffalos, but one of them has a personal grudge to settle with Clint.