During the so-called 'historical turn' in the philosophy of science, philosophers and historians boldly argued for general patterns throughout the history of science. From Kuhn's landmark "Structure of Scientific Revolutions" until the "Scrutinizing Science" project led by Larry Laudan, there was optimism that there could be a general theoretical approach to understanding the process of scientific change. This optimism gradually faded as historians and philosophers began to focus on the details of specific case studies located within idiosyncratic historical, cultural, and political contexts, and abandoned attempts to uncover general patterns of how scientific theories and methods change through time. Recent research has suggested that while we have learned a great deal about the diversity and complexity of scientific practices across history, the push to abandon hope for a broader understanding of scientific change was premature. Because of this, philosophers, historians, and social scientists have become interested in reviving the project of understanding the mechanism of scientific change while respecting the diversity and complexity that has been unveiled by careful historical research over the past few decades. The chapters in this volume consider a particular proposal for a general theory of how scientific theories and methods change over time, first articulated by Hakob Barseghyan in "The Laws of Scientific Change" and since developed in a series of papers by a variety of members of the scientonomy community. The chapters consider a wide range of issues, from conceptual and historical challenges to the posited intellectual patterns in the history of science, to the possibility of constructing a general theory of scientific change, to begin with. Offering a new take on the project of constructing a theory of scientific change and integrating historical, philosophical, and social studies of science, this volume will be of interest to historians, philosophers, and sociologists of science.