As a top priority nationwide, scientific innovation has fascinated numerous researchers who are often however overwhelmed by its concealed paradigm. It is therefore the purpose of the current pamphlet, to fill the gap by offering its readers a sweeping overview of the ignored, if not distorted, fundamentals of modern research enterprise, including the contrast between engineering and scientific problems, and 3 major criteria for the later, which are of practical significance to the most pivotal point among the presumed sequence. Also incorporated are the general strategies in commanding the scientific knowledge pool and in defragmenting the helplessly fragmented intelligence. The well celebrated 4 Fundamental Principles of research innovation, as well as a universal template for the research paper writing, are both exemplified in the appendices. Anecdotes, informal and conversational speech, have been adopted in addition to reinforce the concepts under the streamlined framework, helping to draw a broader readership.