The purpose of this book is to provide an ethnographic description of Ghanaian Diaspora and Protestant congregations in the USA. This book on African diaspora is a "case study" of diaspora missiology in action. Two African diaspora congregations in Europe and five Ghanaian Presbyterian congregations in the USA are highlighted to showcase how "diaspora missiology" is strategically supplementary to the "traditional mission paradigm" in the new demographic reality of the 21st century. Two major considerations compose this case study on Ghanaian diaspora and congregations in the USA: an academic ethnographic description with regard to the distinctive markers of diversity, identity, and receptivity of the Gospel in the multicultural USA society, followed by practical missiological understanding of the formation, development, and mobilization for mission of the USA Ghanaian Protestant Churches.