Riders Under the Moonlight portrays the life of the adrenaline junkie duo on the streets of Brooklyn. The Whitely brothers race motorbikes illegally at night, in the search of pure thrill. Nevertheless, after a tragic accident during a race, one of the brothers has to struggle to survive through a series of events and obstacles thrown on his path. His love for racing soon turns into a race for revenge, as two doctors accompany him throughout his adventures. Fighting off the toughest enemies and injuries, the protagonist revs up the motorbike engine one more time in order to finish off his mission.