A new investigation for the epic protagonist of The Discipline of Penelope. A rich and powerful professor dies suddenly: "natural causes", certifies the doctor. His daughter, however, doesn't believe it and turns to Penelope Spada, a former prosecutor with a mystery behind her and a present of silent despair. The investigation, which at first seems to lead nowhere, turns into a dramatic reckoning with the past, but also an appointment with destiny and the unexpected possibility of changing it.