Reconstructive Transplantation and Regenerative Surgery: The New Frontier is the third volume in the Regenerative and Transplant Medicine Series. This volume captures a decade of transformative progress at the intersection of reconstructive transplantation, regenerative medicine, and tissue engineering—fields that have begun to converge into a bold new frontier: regenerative surgery.
Coedited by internationally recognized leaders in the field, this authoritative work explores cutting-edge advances that are redefining the possibilities for patients with complex tissue loss and functional deficits.
Through comprehensive and original chapters written by global experts, this book charts the latest innovations in vascularized composite allotransplantation (VCA), graft immunomodulation, neurogeneration and diagnostics, ischemia mitigation and tissue preservation, and tissue engineering and biomaterials.
Comprehensive in scope and visionary in approach, Reconstructive Transplantation and Regenerative Surgery: The New Frontier is an essential resource for surgeons, researchers, biomedical engineers, and clinicians.

• Showcases pioneering achievements in face, limb, penile, laryngotracheal, and whole-eye transplantation
• Highlights the advances in cell therapies, gene editing, and localized immunosuppressive delivery systems for graft immunomodulation
• Presents innovations in neurobiologics, biodegradable materials, smart biosensors, and noninvasive imaging for real-time graft surveillance
• Profiles next-generation perfusates and preservation strategies adapted from solid organ transplantation
• Explores the clinical, ethical, and developmental considerations of vascularized composite allotransplantation (VCA) in adolescents and young adults