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Principles of Evolutionary Medicine de Peter Gluckman

Principles of Evolutionary Medicine

Autor Peter Gluckman, Alan Beedle, Tatjana Buklijas, Felicia Low, Mark Hanson
en Limba Engleză Paperback – 17 mar 2016

Bazându-ne pe datele furnizate de OUP OXFORD, reținem că a doua ediție a lucrării Principles of Evolutionary Medicine reprezintă o resursă academică esențială pentru integrarea biologiei evoluționiste în curriculumul medical modern. Credem că relevanța acestui manual rezidă în capacitatea sa de a transforma medicina dintr-o colecție de fapte disparate într-o disciplină integrată, susținută de mecanisme biologice fundamentale. Structura este riguros organizată: prima parte fundamentează teoretic cititorul, indiferent de expunerea sa anterioară la științele evoluției, în timp ce a doua parte aplică aceste principii în arii clinice critice, precum metabolismul, reproducerea și, în premieră pentru această ediție, oncologia.

Merită menționat că volumul extinde considerabil analiza coexistenței umane cu microorganismele, oferind un context evoluționist necesar în era rezistenței la antibiotice și a epidemiilor globale. Principles of Evolutionary Medicine completează perspectiva oferită de Evolutionary Medicine de Stephen C. Stearns, adăugând o dimensiune practică și clinică mai pronunțată, cu un accent deosebit pe căile prin care procesele evolutive modifică riscul de boală și simptomatologia.

În contextul operei autorului Peter Gluckman, acest manual sintetizează temele explorate în lucrări precum The Fetal Matrix sau Fat, Fate, and Disease. Dacă acele titluri se concentrau pe plasticitatea developmentală și originile timpurii ale bolilor netransmisibile, lucrarea de față plasează aceste concepte într-un cadru teoretic universal, adresându-se nu doar cercetătorilor, ci și practicienilor care doresc să înțeleagă „de ce”-ul biologic din spatele patologiilor.

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Specificații

ISBN-13: 9780199663934
ISBN-10: 0199663939
Pagini: 400
Dimensiuni: 190 x 245 x 20 mm
Greutate: 0.86 kg
Ediția:2
Editura: OUP OXFORD
Colecția OUP Oxford
Locul publicării:Oxford, United Kingdom

De ce să citești această carte

Această ediție este indispensabilă studenților la medicină și profesioniștilor din sănătate publică care doresc să înțeleagă rădăcinile biologice ale bolilor. Veți câștiga o perspectivă nouă asupra vulnerabilităților umane, de la cancer la tulburări metabolice, folosind un cadru teoretic ce explică interacțiunea dintre gene, mediu și timp. Este un instrument rar care îmbină rigoarea academică cu aplicabilitatea clinică imediată.

Despre autor

Professor Sir Peter Gluckman este unul dintre cei mai respectați oameni de știință din Noua Zeelandă, fiind profesor de biologie pediatrică și perinatală la Universitatea din Auckland. Fost director al Institutului Liggins pentru Cercetări Medicale, cariera sa este marcată de studii fundamentale privind plasticitatea developmentală și modul în care mediul prenatal influențează sănătatea pe termen lung. Expertiza sa în intersecția dintre biologie, medicină și politici publice este reflectată în structura acestui manual, care pune un accent deosebit pe modul în care evoluția modelează riscurile de boală în societatea contemporană.

Descriere

Evolutionary science is critical to an understanding of integrated human biology and is increasingly recognised as a core discipline by medical and public health professionals. Advances in the field of genomics, epigenetics, developmental biology, and epidemiology have led to the growing realisation that incorporating evolutionary thinking is essential for medicine to achieve its full potential. This revised and updated second edition of the first comprehensive textbook of evolutionary medicine explains the principles of evolutionary biology from a medical perspective and focuses on how medicine and public health might utilise evolutionary thinking. It is written to be accessible to a broad range of readers, whether or not they have had formal exposure to evolutionary science. The general structure of the second edition remains unchanged, with the initial six chapters providing a summary of the evolutionary theory relevant to understanding human health and disease, using examples specifically relevant to medicine. The second part of the book describes the application of evolutionary principles to understanding particular aspects of human medicine: in addition to updated chapters on reproduction, metabolism, and behaviour, there is an expanded chapter on our coexistence with micro-organisms and an entirely new chapter on cancer. The two parts are bridged by a chapter that details pathways by which evolutionary processes affect disease risk and symptoms, and how hypotheses in evolutionary medicine can be tested. The final two chapters of the volume are considerably expanded; they illustrate the application of evolutionary biology to medicine and public health, and consider the ethical and societal issues of an evolutionary perspective. A number of new clinical examples and historical illustrations are included.This second edition of a novel and popular textbook provides an updated resource for doctors and other health professionals, medical students and biomedical scientists, as well as anthropologists interested in human health, to gain a better understanding of the evolutionary processes underlying human health and disease.

Recenzii

This volume will appeal to a broad readership of students and faculty in a variety of disciplines ... I recommend this book highly as a clear and accessible introduction to the growing field of evolution, medicine, and public health.

Notă biografică

Professor Sir Peter Gluckman is a well-known biomedical scientist. Author of over 650 scientific papers and reviews, and of technical and popular science books, his contributions to developmental, endocrine and evolutionary sciences have won him numerous awards and recognition - including Fellowship of the Royal Society (London) and the Order of New Zealand, the country's highest civic honour. He is the only New Zealander elected to the Institute of Medicine of the National Academies of Science (USA) and the Academy of Medical Sciences of Great Britain. Since 2009 Sir Peter has also held the position of Chief Science Advisor to the Prime Minister of New Zealand.Dr Alan Beedle BSc, PhD, is a biochemist who became a professional science editor and writer. He has held senior positions in scientific and medical publishing in the UK, Europe and New Zealand, and has been editor of several high-impact journals in the biomedical sciences. Alan has research interests in the application of evolutionary and developmental biology to human health and disease.Dr Buklijas was trained as a physician in her hometown of Zagreb, Croatia, but then changed career to first study (M.Phil. and PhD) and then work, as a Wellcome Research Fellow, in the Department of History and Philosophy of Science, University of Cambridge. In 2008 she took up a research fellowship at the Liggins Institute where she works on projects related to evolutionary medicine and developmental origins of health and disease, especially from the perspective of the history and philosophy of evolution and development.Dr Felicia Low obtained her PhD in Pathology from the University of Otago, Christchurch, New Zealand. Since taking up a research fellowship with the Office of the Prime Minister's Science Advisory Committee, based at the Liggins Institute, in 2009, her research has focused on the molecular aspects of evolutionary developmental biology. Her other research interests include the effects of early-life factors on later-life risk of non-communicable disease; the utility of developmental epigenetics as a prognostic marker of disease risk, and in informing maternal/early postnatal nutritional advice; and the dissemination and translation of scientific research.Professor Mark Hanson is one of the UK's leading researchers on developmental pathways to disease. He is current President of the International Society for the Developmental Origins of Health and Disease and was a founder member of the Society. He has served on a range of committees in government, charitable and NGOs focusing on the importance of adopting a life course perspective to new ways of reducing the burden of obesity and non-communicable disease globally. He directs the University of Southampton Institute of Developmental Sciences and is British Heart Foundation Professor of Cardiovascular Science there. He holds visiting appointments in several universities overseas. His research concerns several aspects of development and health, ranging from how the environment before and after birth affects the risk of chronic disease to population studies aimed at the early identification of risk, so that timely preventative interventions can be made.