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Practical Statistics in Medicine with R: Understanding Fundamental Concepts through Examples

Autor Konstantinos I. Bougioukas
en Limba Engleză Hardback – 14 mai 2026
Whether you're new to statistical analysis or looking to enhance your analytical skills with the R programming language, this textbook provides comprehensive and practical guidance for understanding fundamental statistical concepts through healthcare examples in R. It is an ideal resource for students, educators, and healthcare researchers seeking a step-by-step first approach to effectively applying R in the analysis of healthcare data.
Readers are introduced to the fundamentals of base R, along with practical methods for data import, preprocessing, and transformation using functions from standard R packages such as base and stats, as well as pipe-friendly functions from the tidyverse collection of packages. Additionally, a chapter is devoted to visualization fundamentals, providing step-by-step guidance on creating data visualizations using the ggplot2 package and its extensions.
The textbook covers the most common statistical tests (e.g., t-test, one-way ANOVA, chi-square test, correlation, and non-parametric tests) and introduces more specialized analyses (e.g., linear regression, survival analysis, reliability of measurement analysis, diagnostic test accuracy and ROC analysis) with examples from biomedical field. Basic mathematical equations for these statistical tests and techniques are provided to enhance understanding. Statistical functions from both “Base” R and the “rstatix” add-on package are often presented side-by-side, fostering engagement and enriching the reader’s coding experience. Designed to be self-contained, this textbook does not require any prior experience with the R programming language, though it assumes a basic understanding of mathematics. (Note: Multivariable modeling and advanced statistical techniques are beyond the scope of this introductory textbook.)
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Specificații

ISBN-13: 9781032600581
ISBN-10: 1032600586
Pagini: 592
Ilustrații: 384
Dimensiuni: 178 x 254 mm
Ediția:1
Editura: CRC Press
Colecția Chapman and Hall/CRC

Public țintă

Professional Training, Undergraduate Advanced, and Undergraduate Core

Notă biografică

 Konstantinos I. Bougioukas received his PhD in Biostatistics and Research Methodology from the Faculty of Medicine at Aristotle University of Thessaloniki, Greece, in 2021. He has extensive experience teaching both basic and advanced Statistics. He has mentored and guided students and researchers from diverse scientific backgrounds—including mathematics, medicine, biology, psychology, and health policy—in applying statistical methodologies and R programming. As a research methodologist and data analyst, he specializes in evidence synthesis—including systematic reviews and meta-analyses, overviews of reviews, and meta-epidemiological studies—as well as advanced data analysis and data visualization techniques. He has authored over 40 peer reviewed research articles published in high-impact biomedical journals. Additionally, he has contributed to the development of three open-source R packages: “ccaR”, “amstar2Vis”, and “musicolor”.

Cuprins

Preface About the Author 1 R via RStudio 2 RStudio Projects 3 R as calculator 4 R functions 5 R packages 6 R objects 7 Atomic vectors 8 Matrices and arrays 9 Lists and data frames  10 Data import, preprocessing, and transformation 11  Data visualization with ggplot2 12 Introduction to Statistics 13 Basic concepts of probability 14 Probability distributions 15 Descriptive statistics 16 Populations and samples 17 Confidence intervals 18 Hypothesis testing 19 Independent samples t-test 20 Wilcoxon-Mann-Whitney test 21 Paired samples t-test 22 Wilcoxon Signed-Rank test 23 One-way Analysis of Variance 24 Kruskal-Wallis test 25 Categorical data analysis 26  Correlation methods 27 Simple linear regression 28 Survival analysis 29 Reliability of measurement 30 Measures of diagnostic test accuracy 31 Receiver Operating Characteristic (ROC) curve Bibliography Index

Descriere

Whether you're new to statistical analysis or looking to enhance your analytical skills with the R programming language, this textbook provides comprehensive and practical guidance for understanding fundamental statistical concepts through healthcare examples in R.