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Practical Hepatic Pathology: A Diagnostic Approach: Pattern Recognition

Editat de Romil Saxena Kevin O. Leslie
en Limba Engleză Hardback – 15 ian 2027
Part of the in-depth and practical Pattern Recognition series, Practical Hepatic Pathology: A Diagnostic Approach, 3rd Edition, helps you arrive at a rapid, accurate diagnosis by using a pattern-based approach. Dr. Romil Saxena leads a team of global hepatic pathology experts who offer practical assistance in identifying all major neoplastic and non-neoplastic diseases of the liver, guiding you from a pathological pattern through the appropriate work-up, around the pitfalls, and to the best diagnosis. Hundreds of high-quality illustrations capture key morphologic patterns for a full range of common and rare conditions and assist in the interpretation of complex diagnostic puzzles, while a unique "visual index" at the beginning of the book directs you to the exact chapter and specific page you need for in-depth diagnostic guidance.
  • Features comprehensive information on major adult and childhood liver diseases, hepatic neoplasms, and pre-neoplastic nodules, including clinical features, laboratory tests, imaging findings, and differential diagnosis
  • Contains superb, high-quality, full-color images-high-resolution histopathologic photomicrographs including special stains, immunohistochemistry and electron microscopy, gross pathology images, radiology and clinical images, schematics and diagnostic algorithms-that illustrate pathognomonic features and common variations
  • Features extensive updates from cover to cover, including coverage of molecular diagnostics, new diagnostic biomarkers and their role in differential diagnosis; newly described histologic entities and disease variants; and integration of targeted and personalized medicine approaches
  • Covers key topics such as metabolic dysfunction-associated liver disease (MAFLD); viral hepatitis and HIV-related liver pathology; drug-induced and toxin-related liver injury; hepatocellular carcinoma and cholangiocarcinoma classification; liver transplantation pathology; fibrosis progression and regression mechanisms; and more
  • Reflects WHO classification of hepatic tumors
  • Includes a suggested reading list in each chapter of the most relevant references, for a quick overview of essential literature
  • An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish after the publication date
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Specificații

ISBN-13: 9780323936408
ISBN-10: 0323936407
Pagini: 750
Dimensiuni: 216 x 276 mm
Ediția:3
Editura: Elsevier
Seria Pattern Recognition


Cuprins

SECTION I: BASIC CONCEPTS IN LIVER PATHOLOGY
1 Microscopic Anatomy, Basic Terms, and Elemental Lesions
2 Special Stains and Immunohistochemistry

SECTION II: INVESTIGATION OF LIVER DISEASE
3 Clinical Features of Liver Disease
4 Laboratory Tests in Liver Disease
5 Imaging of Liver Diseases
6 Liver Biopsy

SECTION III: LIVER DISEASES OF CHILDHOOD
7 Liver Diseases of Childhood

SECTION IV: METABOLIC DISEASES OF THE LIVER
8 Medical Genetics and Biochemistry in Diagnosis and Management
9 Histologic Patterns of Metabolic Liver Diseases
10 Wilson Disease
11 Liver Disease in Alpha-1 Antitrypsin Deficiency
12 Liver Disease in Cystic Fibrosis
13 Liver Disease in Iron Overload
14 Metabolic Dysfunction-Associated Liver Disease

SECTION V: INFECTIOUS DISEASES OF THE LIVER
15 Acute Viral Hepatitis
16 Chronic Viral Hepatitis B
17 Chronic Viral Hepatitis C
18 Chronic Viral Hepatitis Grading and Staging
19 Human Immunodeficiency Virus Infection of the Liver
20 Nonviral Infections of the Liver

SECTION VI: GRANULOMATOUS DISEASES OF THE LIVER
21 Hepatic Granulomas: Differential Diagnosis
22 Hepatic Sarcoidosis

SECTION VII: AUTOIMMUNE HEPATITIS
23 Autoimmune Hepatitis and Overlap Syndromes

SECTION VIII: DRUG AND TOXIN INDUCED LIVER INJURY
24 Metabolism of Drugs and Xenobiotics
25 Liver Injury Due to Drugs and Herbal Agents
26 Alcohol-Related Liver Disease

SECTION IX: DISORDERS OF BILE DUCTS, BILE FORMATION AND SECRETION
27 Fibrocystic Liver Diseases
28 Primary Biliary Cholangitis
29 Primary Sclerosing Cholangitis
30 Loss of Intrahepatic Bile Ducts
31 Intrahepatic Cholestasis: Molecular Physiology of Bile Formation and Secretion
32 Diseases of Bile Formation and Secretion

SECTION X: VASCULAR DISORDERS OF THE LIVER
33 Vascular Disorders of the Liver

SECTION XI: TUMORS AND TUMOR-LIKE LESIONS OF THE LIVER
34 Premalignant and Early Malignant Hepatocellular Lesions in Chronic Hepatitis/Cirrhosis
35 Benign Hepatocellular Tumors
36 Hepatocellular Carcinoma
37 Benign Biliary Tumors and Precursor Lesions
38 Intrahepatic Cholangiocarcinoma
39 Combined Hepatocellular-Cholangiocarcinoma
40 Epithelial Liver Tumors of Childhood
41 Mesenchymal Liver Tumors of Childhood
42 Miscellaneous Liver Tumors and Tumor-like Lesions

SECTION XII: LIVER TRANSPLANTATION
43 Pathology of Liver Transplantation

SECTION XIII: ADVANCED LIVER DISEASE/FIBROSIS
44 Pathophysiology of Advanced Liver Disease
45 Cirrhosis: Term Reconsidered
46 Regression of Liver Fibrosis From Myth to Reality