Clementine Byers is looking for her last line of defense. An insulin dependent diabetic, Clementine struggles to discover her life's purpose. Throughout college, she experiences boys whose dispose her like old syringes, a trail of career paths that lead nowhere, and a church group that promises to cure her from the disease that has haunted her lifetime. When she thinks that she has explored every possible avenue for happiness, Clementine finds hope in a roller derby team, a Canadian holistic medicine specialist, and a star jammer that she remembers from childhood summers at camp. Although she trusts the Lower Your Blood Sugar Naturally pills hawked to her by the specialist, Clementine learns to let go of hope. As she morphs into a hard-hitting roller derby pivot known as Xana Doom, Clementine falls in love with derby, herself, and so much more.