Persister Cells and Infectious Disease
Editat de Kim Lewisen Limba Engleză Paperback – 26 noi 2020
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Specificații
ISBN-13: 9783030252434
ISBN-10: 3030252434
Pagini: 308
Ilustrații: X, 295 p. 34 illus., 28 illus. in color.
Dimensiuni: 155 x 235 x 17 mm
Greutate: 0.47 kg
Ediția:1st ed. 2019
Editura: Springer
Locul publicării:Cham, Switzerland
ISBN-10: 3030252434
Pagini: 308
Ilustrații: X, 295 p. 34 illus., 28 illus. in color.
Dimensiuni: 155 x 235 x 17 mm
Greutate: 0.47 kg
Ediția:1st ed. 2019
Editura: Springer
Locul publicării:Cham, Switzerland
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Cuprins
1. Evolution under antibiotic treatments: interplay between antibiotic persistence, tolerance and resistance.- 2. Antibiotic persisters and relapsing Salmonella enterica infections.- 3. The Biology of Persister Cells in E. coli.- 4. Persister Formation and Antibiotic Tolerance of Chronic Infections.- 5. Persister formation driven by TisB-dependent membrane depolarization.- 6. Toxin-antitoxin systems and persistence.- 7. Nutrient depletion and bacterial persistence.- 8. Genetic determinants of persistence in Escherichia coli.- 9. Persister resuscitation.- 10. Host-pathogen interactions influencing Mycobacterium tuberculosis persistence and drug tolerance.- 11. Drug susceptibility of individual mycobacterial cells.- 12. Antimicrobial drug discovery against persisters.
Notă biografică
Professor Kim Lewis, Northeastern University Boston, Massachusetts, USA
Textul de pe ultima copertă
This volume is a collection of chapters from the leading experts in the relatively new and burgeoning field of persister cell studies. Persisters play a leading role in the recalcitrance of chronic infections, and enable the development of classical antibiotic resistance. The focus of the book is on studies that provide an understanding of the mechanisms of persister formation, antibiotic tolerance and role in disease, at the molecular level.
Caracteristici
Provides an understanding of the mechanisms of persister formation Gives an insight into the role of persisters in infectious disease Discusses the aspects of persister formation in antibiotic resistence