What does it take to develop a peptide-based medicine? What are the key challenges and how are they overcome? What are emerging therapeutics for peptide modalities? This book answers these questions with a holistic story from molecules to medicine, combining the themes of design, synthesis and clinical applications of peptide-based therapeutics and biomarkers. This book will be a valuable resource not only as a reference book for the researcher engaged in academic and pharmaceutical setting, but also a valuable resource to graduate students to understand discovery and development process for peptide-based medicine.