Adoption of electronic health record (EHR) systems in hospitals and physician practices is accelerating. At the same time, however, the lack of usability of EHRs has been identified as an important factor impacting patient safety, and national guidelines have been released to evaluate, test, validate, and document summative usability testing results. In addition, recommendations have been made to improve the usefulness, interoperability, and ability to conduct research of EHRs for pediatric patients.