Recent research recognizes and confirms, that there is a multitude of genetic variations and environmental influences modifying anatomy and function of the brain and mental states of individuals, leading to clinical phenotypes we have gotten used to subsume under the label "schizophrenia". There is probably no other disease, concerning its origin, diagnosis, symptoms personal and sociologic meaning and course, so much depending on geography, climate, diet, hygiene, social, familiar and mental, spiritual and intellectual context, as the states that are summed up under the term Schizophrenia.