This book presents recent research results from a selection of the talks presented in the international symposium “New Trends in Approximation and Applications”, held at Oujda, Morocco, in June 2022. The various chapters describe developments in approximation and its different applications including approximation methods in Numerical Analysis, curves and surfaces in CAGD, interpolation and smoothing, shape modelling and computational topology, subdivision schemes and applications, wavelets, and multiresolution methods. The book is addressed to researchers in all of these areas as well as in general mathematical modelling.