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New Developments in Redox Biology: Fundamental Roles in Health and Disease

Autor Asim K. Duttaroy, Atala Bihari Jena
en Limba Engleză Paperback – 5 aug 2025
New Developments in Redox Biology: Fundamental Roles in Health and Disease serves as a vital resource for understanding the profound impact of the redox system on human biology. In the book, readers are introduced to the intricate balance of oxidative stress, the delicate mechanisms of antioxidant defense, and their pivotal roles in cellular function. This book meticulously unpacks the connections between redox biology and the progression of health, aging, and disease, offering researchers and enthusiasts alike a window into these complex physiological processes.

Aside from illuminating oxidative dynamics, this book delves into emerging trends, therapeutic potential, and the integration of redox principles in developing medical interventions, highlighting its relevance in advancing human health.

  • Explores the fundamental role of redox biology in developmental processes and cellular homeostasis
  • Investigates the impact of oxidative stress on non-communicable diseases, including cancer, metabolic, and autoimmune disorders
  • Examines redox regulation in infectious diseases and host-pathogen interactions
  • Provides detailed insights into redox-related biomarkers and their diagnostic and therapeutic potential
  • Equips readers with cutting-edge knowledge on redox biology through multi-omics approaches
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Specificații

ISBN-13: 9780443438844
ISBN-10: 0443438846
Pagini: 508
Dimensiuni: 191 x 235 x 25 mm
Greutate: 1.04 kg
Editura: ELSEVIER SCIENCE

Cuprins

Section I: The redox theory of developmental biology
1. The role of oxygen availability in embryonic development
2. Balancing of oxidants via antioxidant enzymes in developmental biology
3. Antioxidant-mediated O2 sensing epigenetic regulation
4. Genetic basis of phenotypic plasticity in embryo under stress
5. Cellular signalling cascade regulating embryonic development under oxidative stress
6. Intra-cellular signalling cascade shielding against oxidative stress
7. Stem cell homeostasis and differentiation under oxidative stress
8. Multi-omics signature to oxidative response in cell growth & development

Section II: Redox biology modulating non-communicable diseases
9. Origin of cancer stem cells concerning hypoxia
10. Redox-related biomarkers in tumorigenesis
11. Metabolic disorder and its underlying redox biomarkers
12. Redox regulation of autoimmune disorders
13. Altered redox regulatory mechanisms in neurodegeneration
14. Chronic inflammatory disorders and their redox control reaction
15. Redox-related biomarkers in cardiovascular and immune-mediated inflammatory diseases

Section III: Impact of redox regulation on infectious biology
16. Major redox biomarkers in host-pathogen interaction
17. Redox control in the pathophysiology of zoonoses
18. Antiviral therapeutics and their redox regulation
19. The impact of hypoxia on intestinal invasion by bacterial pathogens
20. Natural antioxidant therapeutics against microbial infection
21. Redox profiling of pathogenic infection in poultry farms