Isabel Kramer's dream of running competitively, frustrated since age seventeen, reveals itself when, on a lark, she joins her daughter in the Bay to Breakers race in San Francisco. Now age sixty, Izzy challenges her misgivings, the sage and well-intentioned advice of family and friends, and prepares for long-distance running. Izzy, a psychiatrist and professor of psychology at UC Berkeley has no illusions about the likelihood of success and the possibility of injury, but amazingly, she outperforms the running world's and her own expectations and trains for the Boston Marathon. Barriers of every type obstruct Izzy's path to Boston. Can they stop her? Supporters of every age see in her the will and the talent to win, and they joyfully join her in the realization of a destiny too long delayed.