In Mystekal, a small, dying town in the Southern California desert, only 75 students attend the old, sometimes creepy high school dubbed "Mystical High," where strange things have been known to happen. Jessie Dalworth and Jinxsy Patterson are juniors and lifelong best friends. At home, Jessie deals with the pain of an absentee mother who has abandoned the family for the lure of Hollywood; Jinxsy contends with a 17th "birthday present" she never wanted or expected. Meanwhile, at school, the unexplained activity begins to escalate when Jinxsy keeps seeing a long-haired guy in the hallway checking her out. Jessie can't see him, but her younger brother, River, can. Then, in English class, a stapler mysteriously flies off teacher Eve Carrow's desk, hitting a student in the face who has just mouthed off to her. The beloved teacher is in the unenviable position of having her brute of a father as principal, so she hates sending any student to his office. As Principal Ernest Carrow begins to terrorize Eve and others more openly, something or someone unseen decides that it's payback time. School is getting stranger, and Jinxsy and Jessie are faced with mind-boggling changes in their home lives that complicate everything. When a string of shocking events expose explosive secrets, decades-long mysteries are finally revealed. Content Warning: Mild sexual content and non-gratuitous profanity