Established in 1638 in a vast Amazonian territory that today encompasses border areas of Ecuador, Peru, Colombia, and Brazil, the missions of Maynas were one of the Society of Jesus’s main enterprises in Spanish America. Jesuit writings provide a unique insight into the seventeenth- and eighteenth-century encounters between Europeans and indigenous peoples. In effect, they shed light on how native Amazonians appropriated elements of Christian religiosity and Iberian urban culture. This book is not only about how indigenous populations experienced life in missions. It is above all a study of how natives actively engaged with the practices and ideas of settlement and religiosity that the Jesuits transmitted.