Mankind is threatened by normal microbial life in 2014 crossing the species barrier from fruit bats to humans, particularly when the Ebola virus, disturbed by new roads entering primeval jungle and then overtaking human slums in Conakry, Guinea, Freetown, Sierra Leone and in Monrovia, Liberia. This book documents the response to Ebola, flu, Bubonic plague and other pathogens. Updated Ebola Viral Disease outbreak in DRC and Congo with crucial updates on Covid-19 2020 and the future of mankind.