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Methods in Modern Biophysics

Autor Bengt Nölting
en Limba Engleză Paperback – 6 oct 2009
Incorporating dramatic recent advances, "Methods in Modern Biophysics" presents a fresh and timely introduction to modern biophysical methods. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, and proteomics. Containing much information previously unavailable in tutorial form, "Methods in Modern Biophysics" employs worked examples and more than 260 illustrations to fully detail the techniques and their underlying mechanisms. The book was written for advanced undergraduate and graduate students, postdocs, researchers, lecturers and professors in biophysics, biochemistry, general biology and related fields.
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Specificații

ISBN-13: 9783642030215
ISBN-10: 3642030211
Pagini: 292
Ilustrații: XVI, 273 p. 287 illus.
Dimensiuni: 155 x 235 x 23 mm
Greutate: 0.41 kg
Ediția:3rd ed. 2010
Editura: Springer Berlin, Heidelberg
Colecția Springer
Locul publicării:Berlin, Heidelberg, Germany

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Descriere

Incorporating recent dramatic advances, this textbook presents a fresh and timely introduction to modern biophysical methods. An array of new, faster and higher-power biophysical methods now enables scientists to examine the mysteries of life at a molecular level. This innovative text surveys and explains the ten key biophysical methods, including those related to biophysical nanotechnology, scanning probe microscopy, X-ray crystallography, ion mobility spectrometry, mass spectrometry, proteomics, and protein folding and structure. Incorporating much information previously unavailable in tutorial form, Nölting employs worked examples and about 270 illustrations to fully detail the techniques and their underlying mechanisms. Methods in Modern Biophysics is written for advanced undergraduate and graduate students, postdocs, researchers, lecturers, and professors in biophysics, biochemistry and related fields.
Special features in the 3rd edition: Introduces rapid partial protein ladder sequencing - an important method for fast and highly sensitive identification of proteins, describes the determination of interaction surfaces in protein complexes by mass spectrometric mapping of binding of chemical linkers - a method to support the high-resolution structural analysis of large macromolecular assemblies.

Cuprins

The three-dimensional structure of proteins.- Liquid chromatography of biomolecules.- Mass spectrometry.- X-ray structural analysis.- Protein infrared spectroscopy.- Electron microscopy.- Scanning probe microscopy.- Biophysical nanotechnology.- Proteomics: high throughput protein functional analysis.- Ion mobility spectrometry.- -Value analysis.- Evolutionary computer programming.- Rapid partial protein ladder sequencing.- Surface labeling analysis of protein interactions.- Conclusions.- References.

Caracteristici

Presents novel information which cannot be found in other textbooks and monographs
Provides one of the most up to date presentations of current biophysics
Only book which covers all of the 10 currently most important biophysical methods
Details exciting recent discoveries and developments in the fields of biophysical nanotechnology, scanning probe microscopy, ion mobility spectrometry, mass spectrometry and proteomics
Introduces rapid partial protein ladder sequencing - an important method for fast and highly sensitive identification of proteins
Describes the determination of interaction surfaces in protein complexes by mass spectrometric mapping of binding of chemical linkers - a method to support the high-resolution structural analysis of large macromolecular assemblies
Well above 250 figures support a quick understanding of technological details plus worked examples in the text and solutions to problems facilitate teaching
Includes supplementary material: sn.pub/extras