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Medical Biochemistry de John W Baynes

Medical Biochemistry

Editat de John W Baynes, Marek H. Dominiczak
en Limba Engleză Paperback – 18 aug 2022
Written by carefully selected global experts, practicing physicians, and educators in the various sub-disciplines of biochemistry, Medical Biochemistry, 6th Edition, offers a unique combination of research and clinical practice tailored to today's integrated courses. Covering clinically relevant topics in greater detail than other texts, this outstanding resource provides a strong overview of traditional areas in medical biochemistry along with state-of-the-art coverage of today's latest developments. You'll learn basic science concepts alongside clinical cases that describe patients likely to be encountered in clinical training, as well as how to use laboratory tests to diagnose and monitor the most important conditions. Thorough yet accessible, this clinically focused text is useful from medical school to clinical practice. 
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Specificații

ISBN-13: 9780323834506
ISBN-10: 0323834507
Pagini: 744
Dimensiuni: 216 x 276 mm
Greutate: 1.6 kg
Ediția:6
Editura: Elsevier

Cuprins

Introduction
1-Introduction
II Molecules and cells
2 Amino Acids and Proteins
3- Carbohydrates and Lipids
4- Cells, Membranes and Transport.
III. Metabolism
5- Hemoglobin and oxygen transport.
6- Catalytic Proteins - Enzymes
7- Coenzymes Vitamins and Minerals
8- Bioenergetics and Oxidative Metabolism
9- Anaerobic metabolism of glucose carbohydrates in the red blood cell
10-The Tricarboxylic Acid Cycle
11-Oxidative Metabolism of Lipids in Liver and Muscle
12- Biosynthesis and Storage of Carbohydrates in Liver and Muscle: Glycogen metabolism and gluconeogenesis
13- Biosynthesis and Storage of Fatty Acids
14-"Metabolism of cholesterol and steroids".
15- Biosynthesis and Degradation of Amino Acids
16- Biosynthesis and Degradation of Nucleotides.
17- Complex Carbohydrates: Glycoproteins.
18- Complex Lipids
19-The Extracellular Matrix.
IV Molecular basis of inheritance
20- Deoxyribonucleic Acid.
21- Ribonucleic Acid.
22- Protein Synthesis and Turnover.
23- Regulation of Gene Expression: Basic Mechanisms
24- Fundamentals of recombinant DNA technology, molecular hybridisation and cloning
25- Genomics, Proteomics and Metabolomics.
V Signalling and growth
26- Membrane Receptors and Signal Transduction
27- Neurotransmitters.
28- Biochemical Endocrinology.
29- Cellular Homeostasis: Cell Growth and Cancer.
30- Aging
VI. Fuels Nutrients and Minerals
31- Digestion and Absorption of Nutrients: The Gastrointestinal Tract.
32- Glucose Homeostasis and Fuel Metabolism: Diabetes Mellitus.
33- Nutrients and diets, malnutrition and obesity
34- Lipoprotein Metabolism and Atherogenesis.
VII. Specialized Tissues and Their Function.
35- The Role of Liver in Metabolism.
36- Kidney: Water and Electrolytes Homeostasis
37- Lung and the Regulation of Hydrogen Ion Concentration (Acid-Base Balance)
38- Energy Metabolism and Contraction Exercise
39- Bone Metabolism and Calcium Homeostasis.
40- Neurochemistry
VIII. Blood and immunity. Clinical biochemistry.
41- Blood and Plasma Proteins.
42- Haemostasis and Thrombosis.
43- Oxidative stress and inflammation.
44-The Immune Response: Innate and adaptive immunity.
Appendix - selected clinical laboratory reference ranges.
Index

Descriere

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Now fully revised, this acclaimed textbook efficiently links basic biochemistry with the day-to-day practice of medicine.
You will learn basic science concepts and see them illustrated by clinical cases that describe patients you will likely encounter in your clinical training. You will also learn about the use of laboratory tests to diagnose and monitor the most important conditions.
Brought to you in a thorough yet accessible manner, this new edition of Medical Biochemistry highlights the latest developments in regulatory and molecular biology, signal transduction, biochemistry and biomarkers of chronic disease, and bioinformatics and the '-omics'. It highlights the most important global medical issues: diabetes mellitus, obesity and malnutrition, cancer and atherosclerotic cardiovascular disease, and addresses the role of nutrition and exercise in medicine.
Featuring a team of expert contributors that includes investigators involved in cutting-edge research as well as experienced clinicians, this book offers a unique combination of research and clinical practice tailored to today's integrated courses.

  • Read organ-focused chapters addressing the biochemistry of the bone, kidney, liver, lungs and muscle; and system-focused ones addressing the biochemistry of the immune and endocrine systems, neurochemistry and neurotransmission, and cancer
  • Download the enhanced, interactive eBook (that comes with the printed book) for unique bonus content and anytime access to the complete contents - extras include:

- a glossary for quick reference review of difficult concepts
- additional clinical images, text and case studies to further relate essential concepts to modern practice
- links to important further resources - including videos, databases, key guidelines and related literature
- 150+ multiple-choice and USMLE-style questions to test your understanding and aid exam preparation