**Selected for 2025 Doody’s Core Titles® in Radiation Oncology**

Machine Learning and Artificial Intelligence in Radiation Oncology: A Guide for Clinicians is designed for the application of practical concepts in machine learning to clinical radiation oncology. It addresses the existing void in a resource to educate practicing clinicians about how machine learning can be used to improve clinical and patient-centered outcomes. This book is divided into three sections: the first addresses fundamental concepts of machine learning and radiation oncology, detailing techniques applied in genomics; the second section discusses translational opportunities, such as in radiogenomics and autosegmentation; and the final section encompasses current clinical applications in clinical decision making, how to integrate AI into workflow, use cases, and cross-collaborations with industry. The book is a valuable resource for oncologists, radiologists and several members of biomedical field who need to learn more about machine learning as a support for radiation oncology.

• Presents content written by practicing clinicians and research scientists, allowing a healthy mix of both new clinical ideas as well as perspectives on how to translate research findings into the clinic
• Provides perspectives from artificial intelligence (AI) industry researchers to discuss novel theoretical approaches and possibilities on academic collaborations
• Brings diverse points-of-view from an international group of experts to provide more balanced viewpoints on a complex topic