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Lupus Nephritis de Edmund J. Lewis

Lupus Nephritis: Oxford Clinical Nephrology Series

Editat de Edmund J. Lewis, Melvin M. Schwartz, Stephen M. Korbet, Daniel Tak Mao Chan
en Limba Engleză Paperback – 4 noi 2010

Sub coordonarea unei echipe de experți formată din Edmund J. Lewis, Melvin M. Schwartz, Stephen M. Korbet și Daniel Tak Mao Chan, această a doua ediție a lucrării Lupus Nephritis sintetizează expertiza clinică acumulată în centre universitare de prestigiu. Observăm o abordare riguroasă a inflamației renale severe, corelată direct cu prognosticul negativ al pacienților diagnosticați cu Lupus Eritematos Sistemic (LES).

În cadrul volumului publicat de OUP OXFORD, ne-a atras atenția modul în care autorii integrează progresele revoluționare în farmacoterapia bolilor autoimune, survenite de la prima ediție. Textul analizează minuțios mecanismele complexe prin care sistemul imunitar provoacă leziuni renale, oferind o bază științifică pentru testarea terapiilor specifice care întrerup răspunsul imun. Structura celor 342 de pagini este susținută vizual de 55 de ilustrații și o secțiune dedicată planșelor color, esențiale pentru interpretarea corectă a trăsăturilor microscopice.

Clinicienii care folosesc Lupus de Daniel J. Wallace ca referință generală pentru reumatologie vor găsi aici o specializare profundă pe segmentul nefrologic, completând tabloul clinic cu detalii despre managementul cronic al afectării renale. Față de lucrări precum Lupus Renal Involvement, acest titlu din Oxford Clinical Nephrology Series pune un accent mai mare pe corelația dintre studiile clinice recente și practica de zi cu zi, oferind protocoale actualizate de clasificare a nefritei lupice. Apreciem rigoarea cu care sunt tratate anomaliile imunologice moștenite, transformând volumul într-un instrument indispensabil pentru nefrologi și reumatologi.

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Specificații

ISBN-13: 9780199568055
ISBN-10: 0199568057
Pagini: 342
Ilustrații: 55 black and white illustrations and an 8-page colour plate section
Dimensiuni: 157 x 234 x 21 mm
Greutate: 0.61 kg
Ediția:2nd edition.
Editura: OUP OXFORD
Colecția OUP Oxford
Seria Oxford Clinical Nephrology Series

Locul publicării:Oxford, United Kingdom

De ce să citești această carte

Această lucrare se adresează medicilor nefrologi și reumatologi care gestionează cazuri complexe de LES. Cititorul câștigă acces la cele mai noi metode de clasificare și scheme de tratament validate prin studii clinice recente. Este o resursă esențială pentru a înțelege cum terapiile țintite pot modifica prognosticul renal și pentru a rafina îngrijirea pe termen lung a pacienților cu afectare renală severă.

Despre autor

Coordonatorul principal, Edmund J. Lewis, este un nume de referință în nefrologia academică, recunoscut pentru contribuțiile sale în studiul bolilor renale autoimune. Alături de Melvin M. Schwartz, patolog renumit, și colegii lor Stephen M. Korbet și Daniel Tak Mao Chan, aceștia formează un grup de editori cu o vastă experiență în cercetarea clinică și tratamentul nefritei lupice. Expertiza lor combinată asigură o perspectivă multidisciplinară asupra bolii, îmbinând patologia microscopică cu managementul clinic avansat.

Descriere

Severe inflammation of the kidney can indicate the serious, negative prognosis of lupus nephritis when present in conjunction with systemic lupus erythematosus (SLE), a chronic autoimmune connective tissue disease that can affect any part of the body, most often harming the heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous system. This book pulls together in one comprehensive reference the current knowledge regarding the inherited and immunologic abnormalities that have been identified in SLE, with specific reference to the development of renal disease and the way in which these factors may impact upon the chronic care of these patients. Since publication of the first edition in 1999, the discipline of medicine has experienced some revolutionary changes in the way drugs are used to treat to immune system diseases. On the basis of careful analysis of physical make-up, the immune system, and microscopic features of the human body, it has become clear that multiple components of the immune system are responsible for renal injury and that any given patient can experience a combination of these mechanisms. With this in mind, specific therapies can be tested, and drugs that interrupt the immune response in highly specific ways are being scrutinized for their value in lupus nephritis. This new edition reflects the updated methods of classification and advances in treatment options for SLE, and covers recent clinical trials to help treat patients using the most up-to-date knowledge available. It takes a practical approach throughout, and will be of interest to those working with patients with lupus nephritis, and those who manage their everyday care.

Notă biografică

Edmund J. Lewis, M.D. is the Muehrcke Family Professor of Nephrology at Rush University Medical Center. Much of his career has been devoted to the study of immunopathologic mechanisms of glomerular disease, particularly lupus nephritis. He was an active participant in the International Study of Kidney Disease in Children (ISKDC), and as a member of the Pathology Committee he co-authored the first World Health Organization Classification of lupus nephritis. This led him to organize the Collaborative Study Group, whose initial study of plasmapheresis in severe lupus nephritis led to many important observations regarding clinical and histologic features which determine response to therapy in this patient population. In 2007, Dr. Lewis received the Belding Scribner Award of the American Society of Nephrology "for outstanding contributions to nephrology in the area of clinical practice and patient care". Professor Schwartz completed his M.D. at the University of Minnesota in 1967, before taking a Pathology Residency at the Mallory Institute of Pathology between 1968 and1971, and completing a Renal Pathology Fellowship, also at the Mallory Institute of Pathology, in 1973. He became Professor Pathology at Rush University Medical Center in1984.Stephen M. Korbet graduated from Rush Medical College in 1979 and did his internship, residency and Fellowship training at Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois. He is board certified in Internal Medicine and Nephrology. Dr. Korbet has received many prestigious honors and awards. He holds the endowed chair of the "Lester and Muriel Anixter Professor of Nephrology" at Rush Medical College. He is also currently the Medical Director of Circle Medical Management Dialysis Facility in Chicago as well as the Division Chief of the Section of Nephrology, Rush University Medical Center. Chicago, IL He has also been actively involved in clinical research involving kidney disease and dialysis since 1986 until the present date.Daniel Tak Mao Chan graduated from the University of Hong Kong in 1985, and received training in nephrology and internal medicine in Hong Kong and at the Guy's Hospital in London, U.K. He is a Fellow of the Royal Colleges of Physicians in U.K. He is currently Personal Chair and Yu Foundation Endowed Professor in Nephrology at the Department of Medicine, and the Associated Dean at the Li Ka Shing Faculty of Medicine, University of Hong Kong. He was President of the Asian Pacific Society of Nephrology from 2008 to 2010. He is an Executive Committee member of the Asian Society of Transplantation, and has previously served as President of the Hong Kong Society of Transplantation. He pioneered the use of mycophenolate mofetil in the treatment of severe lupus nephritis. In addition to the treatment and immuno-pathogenesis of lupus nephritis, his other research interests include viral hepatitis in patients with renal failure.