A little dog finds himself alone in the vastness of Manhattan after his owner suffers an accident on the street. His two-year journey takes him to familiar neighborhoods and famous landmarks, but also into New York City's more cheerless, sinister underside. He grows streetwise as a succession of safe havens succumb to relentless peril. Along the way he encounters other dogs, mostly larger breeds like pit bulls, some trained fighters, others gentle and caring whose family he joins. A resilient, tough little dog who feels love and hurt simply, as dogs do, he perseveres in the hope that one day he will get back home.