Laboratory animals are fundamental in learning and teaching within the various areas of neuroscience research. This from its proper management, animal welfare, standardization of protocols, use of the best biomodel in exprimentation. There are many different areas of study within neurosciences today. However, any use of any biomodel must be based on the context of the three Rs (Refinement, Reduction and Replacement). The objective of this book is to make known through different chapters the use of different laboratory animals in standardized research lines applied to neurosciences in different contexts and applications in basic research.