This textbook is conceived for a one-semester course at the upper undergraduate or freshman graduate level. The book was written With the fact that nanotechnology is a vast field where the applications range from paint to nanomedicine, through plasmonics and catalysis. An introductory course must be a compromise between a quantitative and a qualitative treatment. For that, this textbook is more quantitative than others in the market, which often do not treat the key concepts with enough depth. This textbook focuses on the key physical and chemical principles and uses many formulas and equations within with the one-semester time constraint.