This book constitutes the proceedings of the Sino-foreign-interchange Workshop on Intelligence Science and Intelligent Data Engineering, IScIDE 2011, held in Xi'an, China, in October 2011. The 97 papers presented were carefully peer-reviewed and selected from 389 submissions. The IScIDE papers in this volume are organized in topical sections on machine learning and computational intelligence; pattern recognition; computer vision and image processing; graphics and computer visualization; knowledge discovering, data mining, web mining; multimedia processing and application.