Informatics In Proteomics
Editat de Sudhir Srivastavaen Limba Engleză Paperback – 23 oct 2019
Through computer simulations, scientists can determine more about how diseases affect cells, predict how various drug interventions would work, and ultimately use proteins as therapeutic targets. This book first addresses the infrastructure needed for public protein databases. It discusses information management systems and user interfaces for storage, retrieval, and visualization of the data as well as issues surrounding data standardization and integration of protein sequences recorded in the last two decades. The authors subsequently examine the application of statistical and bioinformatic tools to data analysis, data presentation, and data mining. They discuss the implementation of algorithms, statistical methods, and computer applications that facilitate pattern recognition and biomarker discovery by integrating data from multiple sources.
This book offers a well-rounded resource of informatic approaches to data storage, retrieval, and protein analysis as well as application-specific bioinformatic tools that can be used in disease detection, diagnosis, and treatment. Informatics in Proteomics captures the current state-of-the-art and provides a valuable foundation for future directions.
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Specificații
ISBN-13: 9780367392550
ISBN-10: 0367392550
Pagini: 436
Dimensiuni: 156 x 234 mm
Greutate: 0.92 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
ISBN-10: 0367392550
Pagini: 436
Dimensiuni: 156 x 234 mm
Greutate: 0.92 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
Public țintă
Academic and Professional Practice & DevelopmentCuprins
The Promise of Proteomics: Biology, Applications, and Challenges; Proteomics Technologies; Creating a National Virtual Knowledge Environment for Proteomics and Information Management; Public Protein Databases and Interfaces; Proteomics Knowledge Databases: Facilitating Collaboration and Interaction between Academia, Industry, and Federal Agencies; Proteome Knowledge Bases in the Context of Cancer; Data Standards in Proteomics: Promises and Challenges; Data Standardization and Integration in Collaborative Proteomics Studies; Informatics Tools for Functional Pathway Analysis Using Genomics and Proteomics; Data Mining in Proteomics; Protein Expression Analysis; Nonparametric, Distance-Based, Supervised Protein Array Analysis; Protein Identification by Searching Collection of Sequences with Mass Spectrometric Data; Bioinformatics Tools for Differential Analysis of Proteomic Expression Profiling Data from Clinical Samples; Sample Characterization Using Large Data Sets; Computational Tools for Tandem Mass Spectrometry-Based High-Throughput Quantitative Proteomics; Pattern Recognition Algorithms and Disease Biomarkers; Statistical Design and Analytical Strategies for Discovery of Disease-Specific Protein Patterns; Image Analysis in Proteomics; Index
Descriere
A well-rounded resource for those involved with informatics tools useful in disease detection, diagnosis, and treatment, Informatics in Proteomics examines the application of statistical and bioinformatic tools in data analysis, presentation, and mining. It discusses the implementation of algorithms, statistical methods, and computer applications that facilitate pattern recognition and biomarker discovery by integrating data from multiple sources. The book also addresses the infrastructure needed for public protein databases, information management systems and user interfaces, as well as issues surrounding data standardization and integration of protein sequences recorded in the last two decades.