Will & James Woltzberg are on the verge of a medical breakthrough that will change mankind. But when one of their scientists is murdered, their luck begins to change. As the investigation into the murder continues, Will is approached by Monica Rowe, sexy CEO of Sander Pharmaceuticals, with an offer to purchase his company. When Will declines, Monica turns up the pressure-by all means available. Will and James think they have it all under control, but when Department of Homeland Security Agent Leah Peterson comes knocking, Will and James realize their breakthrough could be part of one of the deadliest terrorist attacks in history. Meanwhile, halfway across the world, television star Nigel Drake watches in horror as the world around him suddenly starts to change.......