In this book, the authors present topical research in the study of the clinical pharmacology, medical uses, and adverse effects of ibuprofen. Topics discussed include the occurrence, ecotoxicity and water remediation technologies of ibuprofen in the aquatic environment; associated adverse drug reaction in ibuprofen use; hybrid multifunctional ibuprofen drugs; a pharmaceutical nanotechnology approach to ibuprofen delivery; vibrational dynamics and chiral properties of racemate and pure enantiomers of ibuprofen complexed in cyclodextrins; therapeutic effects of ibuprofen on transgenic mice models of neurodegenerative diseases; and the use of ibuprofen for pain relief in gynaecology.