This is a comprehensive treatment of hypoglycemia written by a leading investigator in the field who is also an active clinician. It applies up-to-date concepts of the physiology of glucose counterregulation-the mechanisms that normally prevent or rapidly correct hypoglycemia and thus defend the brain from its devestating effects-and of the pathophysiology of those mechanisms which were largely unknown when previous books on the topic were published, to the diagnosis and treatment of the clinical problem. While its early chapters provide a detailed scientific background, its clinical chapters (on hypoglycemia in diabetes mellitus, the hypoglycemic disorders and the approach to the patient with hypoglycemia) provide much practical guidance for physicians.