A hurricane of terrifying intensity is looming over Florida. Along a state highway, a handful of foolhardy souls trying to outrun the storm are forced to seek shelter in an abandoned house.

Thrown together by nothing more than chance, this disparate bunch of misfits includes an undercover agent seeking revenge for a personal tragedy, a burgeoning criminal in over his head, a beautiful young widow trying to start over, and a businessman whose life's work is crumbling before his eyes. Their refuge from the awesome power of nature becomes a sort of grand and grisly hotel - especially once the invisible hand of flying death descends.