Our volume examines the potential for change during the life course and across generations. We address the possibilities for promoting healthy development from infancy to adulthood in three key domains: human capital, partnership behavior, and child and adolescent development. Drawing from the disciplines of economics, demography, sociology, psychology, and psychiatry, our volume takes a multidisciplinary approach to review relevant empirical work regarding aspects of change and continuity, and the ways in which policies and programs might bring about change. We feature chapters from leading researchers in five countries to address these important issues. The main purpose of our volume is to link and integrate the lessons learned from multiple disciplines about change and continuity in order to examine how our nations can improve life chances.