Guide to Clinical Resource Management is the first in a series of thre e handbooks. Clinical Resource Management (CRM) is the next stage in t he evolution of restructuring/reengineering. It involves advanced prac tice clinical case management, restructuring the quality and utilizati on departments, and creating multidisciplinary clinical service teams that cross the traditional boundaries of hospital departments, clinics, and physicians. The handbook details the design, implementation, and evaluation of a CRM program in an institution well advanced in restru cturing the delivery of acute care and offers a strategy for surviving and succeeding in a managed care environment.