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Glycoimmunology

Editat de Azita Alavi, John S. Axford
en Limba Engleză Paperback – 21 oct 2012

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Specificații

ISBN-13: 9781461357681
ISBN-10: 1461357683
Pagini: 308
Ilustrații: X, 295 p.
Dimensiuni: 178 x 254 x 17 mm
Greutate: 0.58 kg
Ediția:Softcover reprint of the original 1st ed. 1995
Editura: Springer
Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

1. A Review of the Biological Significance of Carbohydrates on Glycoproteins and Methods for Their Analysis.- 2. The Different Faces of Disease: FACE® Diagnosis of Disease.- 3. Chemometrics of Oligosaccharide Analysis: Parameterization of HPLC of PA-Oligosaccharides.- 4. Molecular Modelling of Glycoproteins by Homology with Non-Glycosylated Protein Domains, Computer Simulated Glycosylation and Molecular Dynamics.- 5. Control and Function of Complex-Type Oligosaccharide Synthesis: Novel Variants of the LacNAc Pathway.- 6. The Regulation of Cell- and Tissue-Specific Expression of Glycans by Glycosyltransferases.- 7. The Genetic Regulation of Sialyl-Lex Expression in Haemopoietic Cells.- 8. Murine ?1,4-Galactosyltransferase: Analysis of a Gene that Serves both a Housekeeping and a Cell Specific Function.- 9. Cell Surface ?1,4-Galactosyltransferase: A Signal Transducing Receptor?.- 10. O-Linked N-Acetylglucosamine: The “Yin-Yang” of Ser/Thr Phosphorylation?: Nuclear and Cytoplasmic Glycosylation.- 11. Heparan Sulphate and Protein Recognition: Binding Specificities and Activation Mechanisms.- 12. Glycosylation and Maturation Rate of Membrane and Secretory Forms of Human CD8? Glycoprotein: Implications in the Activation of T-Lymphocytes.- 13. Lectin-Carbohydrate Interactions in Disease: T-Cell Recognition of IgA and IgD; Mannose Binding Protein Recognition of IgG0.- 14. Glycosylation of Antibody Molecules: A Small Step for Structure, a Leap for Function.- 15. The Effects of Altered Glycosylation of IgG on Rheumatoid Factor-Binding and Immune Complex Formation.- 16. Agalactosylation by Reactive Oxygen Species and Fc Related Changes to Function.- 17. An Introduction to Glycosylation and Rheumatic Disease: What Is the Current State of Play.- 18. Abnormalities in theGlycosylation of IgG and Its Clinical Utility.- 19. ?1,4-Galactosyltransferase Variations in Rheumatoid Arthritis.- 20. Significance and Molecular Basis for IgG Glycosylation Changes in Rheumatoid Arthritis.- 21. Immunology of Chondroitin/Dermatan Sulfate.- 22. IgA Glycosylation and Disease.- 23. IgA Nephropathy: A Disease of Incomplete IgA 1 Glycosylation?.- 24. ?1-Acid Glycoprotein: A Natural Occurring Anti-Inflammatory Molecule?.- 25. Haptoglobin: A Potential Reporter Molecule for Glycosylation Changes in Disease.- 26. Inflammatory Cytokines Controlling Branching of N-Heteroglycans of Acute Phase Protein.- 27. Cell Cycle-Related Protein Kinases and T Cell Death.- 28. Sialomucins in Inflammation and Hematopoiesis.- 29. Synthesis and Biological Activity of Oligosaccharide Libraries.- 30. In Vivo Targeting Function of N-Linked Oligosaccharides: Pharmacokinetic and Biodistribution of N-Linked Oligosaccharides.- 31. Studies on Selectin-Carbohydrate Interactions.