Welcome to the 29th edition of the Great Lakes Symposium on VLSI (GLSVLSI) 2019, held between May 9-11, 2019 at Tysons Corner, VA in the Washington, DC metropolitan area. GLSVLSI is a premier venue for the dissemination of manuscripts of the highest quality in all areas related to VLSI, devices, and system-level design. The location of this year's GLSVLSI is Washington, DC, visiting the east coast of the US, not too far from the "Great Lakes" region of the USA, especially given the global stretch of GLSVLSI host cities within the past decade. Conference will be held at Tysons Corner Marriott located in Tysons Corner, VA, a short ride from downtown Washington DC. ACM GLSVLSI 2019 is presented through the collaborative effort of a 15+ member organizing committee with 100+ technical program committee members. The Technical Program Committee Chairs, Tinoosh Mohsenin and Weisheng Zhao, have put together the 2019 installment of the traditionally strong ACM SIGDA GLSVLSI program. The program is structured around the following eight tracks, with GLSVLSI welcoming the International Conference on Microelectronic Systems Education (MSE) for GLSVLSI attendees as one of the tracks in 2019: 1. VLSI Design (Track Chairs Selcuk Kose, Inna Partin-Vaisband) 2. VLSI Circuits and Power Aware Design (Track Chairs Deliang Fan, Swaroop Ghosh) 3. Computer-Aided Design (Track Chairs Yanzhi Wang, Jianlei Yang) 4. Testing, Reliability, Fault Tolerance (Track Chairs Sandip Ray, Benjamin Schaefer) 5. Emerging Computing & Post-CMOS Technologies (Track Chairs Sorin Cotofana, Yue Zhang) 6. Hardware Security (Track Chairs JV Rajendran, Patrick Schaumont) 7. VLSI for Machine Learning and Artificial Intelligence (Track Chairs Philip Brisk, Amey Kulkarni) 8. Microelectronics Systems Education (Track Chairs Tina Hudson, Bradley Minch)