Gilda Radner died of ovarian cancer on May 20, 1989. When the New York Times published "Research Links Diet and Infertility Factors to Ovarian Cancer," by medical writer Larry Altman, on July 25, 1989, Gilda's husband, Gene Wilder, wrote the author to ask some pointed questions. Altman urged him to contact Dr. M. Steven Piver at the Roswell Park Cancer Institute in Buffalo, New York.

Wilder and Piver met via telephone and immediately recognized their shared common desire. From that time, they have worked together to communicate to the general public what is known about ovarian cancer. When Dr. Piver decided to write Gilda's Disease, he asked Wilder to help him by sharing what he had learned during Gilda's struggle so that others might benefit from their ordeal. Wilder and Piver have worked diligently to ensure that the material provided here is accessible and informative without being too scary. The result is a book that offers both medical and personal insights into ovarian cancer.

All royalties will benefit two organizations honoring Gilda's memory: "Gilda's Club," a free, nonresidential support community located in New York City for people with cancer, their families, and friends; and "The Gilda Radner Familial Ovarian Cancer Registry" in Buffalo, New York, which tracks women with a family history of ovarian cancer and advises them of their risk for developing the disease and methods of prevention.