GANI & SEAN follows two assassins whose paths cross when one fails to fulfill her contract to kill the other. Sean LePen misses her first and second shots when she realizes her target, Gani Jaksic is a man she admires for years, since her days in weapons training under his tutelage. When her boss Kristoff Koczella - the brutal and bizarre Chicago kingpin - discovers his assassin's mistake, he hires "the voice" to kill Sean and her target, Gani. Sean flees across country with both Gani and "the voice" on her trail. When she escape? Will Gani?