Jules O'Brien and Michelle Davis have been best friends since third grade, when Jules and her single mother moved from Cleveland to the small Alabama town where Michelle's family has lived for generations. Now in their mid-twenties, the childhood friends live miles and worlds apart. When Jules agrees to be the maid of honour in Michelle's wedding, she quickly realizes just how different the two have become. Over the years, their passions and politics have diverged, and in the middle of wedding-planning squabbles, they feel more like strangers than the sisters they once were.