This book constitutes the thoroughly refereed post-conference proceedings of the 22nd International Conference on Financial Cryptography and Data Security, FC 2018, held in Nieuwport, Curaçao, in February/ March 2018. The 27 revised full papers and 2 short papers were carefully selected and reviewed from 110 submissions. The papers are grouped in the following topical sections: Financial Cryptography and Data Security, Applied Cryptography, Mobile Systems Security and Privacy, Risk Assessment and Management, Social Networks Security and Privacy and much more.